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Comme avec d'autres médicaments qui inhibent l'angiotensine II ou ses effets, l'administration concomitante de médicaments retenant le potassium (par exemple les diurétiques épargneurs de potassium : amiloride, triamtérène, spironolactone) ou susceptibles d'augmenter les taux de potassium (par exemple l'héparine), de suppléments potassiques ou de substituts de sel contenant du potassium peut provoquer une élévation de la kaliémie!